Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid

Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid - Names and Identifiers

Name	Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid
Synonyms	RARECHEM DK FD C007 Fmoc-b-Phe(4-NO2)-OH FMOC-BETA-PHE(4-NO2)-OH FMOC-D-PHG(4-NO2)-(C*CH2)OH Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid FMOC-(S)-3-AMINO-3-(4-NITRO-PHENYL)-PROPANOIC ACID FMOC-(S)-3-AMINO-3-(4-NITRO-PHENYL)-PROPIONIC ACID (S)-3-(9-FLUORENYLMETHOXYCARBONYLAMINO)-3-(4-NITRO-PHENYL)-PROPIONIC ACID (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid
CAS	501015-25-4

Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid - Physico-chemical Properties

Molecular Formula	C24H20N2O6
Molar Mass	432.43
Storage Condition	2-8°C

Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid - Introduction

Fmoc-S-3-Amino-3-(4-nitro-phenyl)-propionic acid is an organic compound with the following properties:

1. Appearance: white crystalline powder.
2. molecular formula: C? H? N? O? S.
3. Molecular weight: 451.45g/mol.
4. Solubility: Fmoc-S-3-amino -3-(4-nitrophenyl) propionic acid has good solubility in organic solvents such as dimethyl sulfoxide (DMSO) and difluoromethane (DCM).

Fmoc-S-3-amino -3-(4-nitrophenyl) propionic acid is commonly used in solid-phase synthesis methods in organic synthesis, and its main uses include:
1. Protein and peptide synthesis.
2. In solid phase synthesis, it can be used as a protecting group to protect active functional groups such as amino groups.
3. It can also be used in drug research and development, biological research and chemical biology and other fields.

Fmoc-S-3-amino -3-(4-nitrophenyl) propionic acid is generally obtained by organic synthesis methods, the specific steps are as follows:
1. In an appropriate solvent, add sodium borohydride (NaBH¾) and 2-chloroethyl sodium carbonate (NaOEt) at low temperature.
2. Add 3-amino -3-(4-nitrophenyl) propanol and heat to react.
3. add sulfur trioxide (SO) and continue to heat the reaction.
4. After cooling, add Fmoc-Cl (sodium difluoroformamide).
5. Filter and obtain the final product by appropriate crystallization method.

Regarding safety information, Fmoc-S-3-amino -3-(4-nitrophenyl) propionic acid is an organic compound and requires the following precautions:
1. in the operation should wear appropriate protective equipment, such as gloves, protective glasses, etc.
2. Avoid inhalation or contact with skin and eyes. If contact occurs, rinse immediately with water and seek medical attention.
3. in the operation to maintain good ventilation conditions.
4. Avoid direct sunlight during storage and should be stored in a dry and cool place.
5. in use or disposal should comply with the local chemical management regulations.

It should be noted that the information provided above is for reference only, and the specific experimental operation and use safety measures should follow the corresponding safety guidelines and laboratory regulations.

Last Update：2024-04-09 20:02:46